Hironobu Hamada Selected Research

Adenocarcinoma of Lung

1/2022	First-line osimertinib treatment in a patient with lung adenocarcinoma with coexisting epidermal growth factor receptor G719S and de novo T790M mutations.
2/2021	Alectinib-induced Immune Hemolytic Anemia in a Patient with Lung Adenocarcinoma.
9/2020	Two Cases of Cranial Nerve Metastasis Treated with Radiotherapy and Chemotherapy in Patients with Lung Adenocarcinoma.
3/2019	Cerebral embolism during edoxaban administration for venous thromboembolism in a patient with lung adenocarcinoma: A case report.
1/2019	Inhibition of PAI-1 limits chemotherapy resistance in lung cancer through suppressing myofibroblast characteristics of cancer-associated fibroblasts.
1/2018	Nivolumab-induced severe pancytopenia in a patient with lung adenocarcinoma.
6/2017	[A Case of Central Diabetes Insipidus That Was Caused by Pituitary Metastasis of Lung Adenocarcinoma and Was Controlled by Radiation Therapy].
1/2012	Krebs von den Lungen-6 (KL-6) is a prognostic biomarker in patients with surgically resected nonsmall cell lung cancer.
6/2007	Circulating KL-6/MUC1 mucin carrying sialyl Lewisa oligosaccharide is an independent prognostic factor in patients with lung adenocarcinoma.

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Hironobu Hamada Research Topics

Disease

28	Neoplasms (Cancer) 11/2023 - 11/2004
19	Interstitial Lung Diseases (Interstitial Lung Disease) 11/2023 - 02/2002
18	Lung Neoplasms (Lung Cancer) 11/2023 - 10/2008
18	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 02/2023 - 08/2007
11	Fibrosis (Cirrhosis) 01/2024 - 01/2017
10	Idiopathic Pulmonary Fibrosis 05/2024 - 02/2002
10	Lung Injury 05/2024 - 12/2002
10	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2024 - 01/2016
10	Malignant Mesothelioma 01/2022 - 03/2006
9	Adenocarcinoma of Lung 01/2022 - 06/2007
8	Asthma (Bronchial Asthma) 10/2023 - 03/2006
6	Pneumonia (Pneumonitis) 10/2022 - 11/2004
6	Bronchiectasis 02/2021 - 04/2013
5	Acute Lung Injury 05/2024 - 01/2013
5	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 11/2021 - 02/2002
5	Inflammation (Inflammations) 01/2021 - 01/2017
5	Neoplasm Metastasis (Metastasis) 09/2020 - 02/2002
4	Disease Progression 07/2022 - 06/2010
3	Chronic Obstructive Pulmonary Disease (COPD) 09/2022 - 12/2018
3	Dyspnea (Shortness of Breath) 09/2022 - 01/2013
3	Respiratory Insufficiency (Respiratory Failure) 02/2022 - 01/2007
3	Emphysema 04/2021 - 01/2016
3	Extrinsic Allergic Alveolitis (Hypersensitivity Pneumonitis) 01/2019 - 12/2002
3	Pleural Effusion (Pleural Effusions) 08/2012 - 03/2006
2	Carcinogenesis 11/2022 - 10/2020
2	Disseminated Intravascular Coagulation 02/2021 - 01/2014
2	Venous Thromboembolism 02/2021 - 03/2019
2	Intracranial Embolism 01/2020 - 03/2019
2	Adenocarcinoma 01/2019 - 06/2007
2	Sepsis (Septicemia) 01/2018 - 01/2013
2	Neurogenic Diabetes Insipidus (Central Diabetes Insipidus) 06/2017 - 02/2002
2	Bacterial Pneumonia 01/2016 - 02/2002
2	Mesothelioma 02/2013 - 04/2010
1	Rhinosinusitis 10/2023
1	Dysbiosis 10/2023
1	Acquired Immunodeficiency Syndrome (AIDS) 09/2023

Drug/Important Bio-Agent (IBA)

12	Biomarkers (Surrogate Marker)IBA 05/2024 - 02/2002
9	Bleomycin (Blenoxane)FDA LinkGeneric 05/2024 - 01/2016
8	LigandsIBA 07/2022 - 01/2016
6	ErbB Receptors (EGF Receptor)IBA 02/2023 - 06/2008
6	Proteins (Proteins, Gene)FDA Link 01/2023 - 02/2002
6	Cisplatin (Platino)FDA LinkGeneric 02/2021 - 03/2006
5	CytokinesIBA 11/2023 - 01/2017
5	Plasminogen Activator Inhibitor 1IBA 02/2023 - 01/2016
5	Plasminogen Activators (Plasminogen Activator)IBA 02/2023 - 01/2016
5	HMGB1 Protein (HMG1)IBA 01/2023 - 01/2020
5	AntibodiesIBA 01/2022 - 06/2007
4	Mucin-1 (CA 15-3 Antigen)IBA 01/2019 - 03/2006
4	AsbestosIBA 02/2013 - 03/2006
3	Glycoproteins (Glycoprotein)IBA 05/2024 - 03/2006
3	Adrenal Cortex Hormones (Corticosteroids)IBA 09/2023 - 04/2010
3	Messenger RNA (mRNA)IBA 01/2023 - 01/2021
3	SteroidsIBA 12/2022 - 08/2003
3	Immunoglobulin G (IgG)IBA 12/2022 - 01/2012
3	Receptor for Advanced Glycation End ProductsIBA 01/2022 - 01/2017
3	AntigensIBA 04/2021 - 01/2017
3	pembrolizumabIBA 03/2020 - 03/2019
3	Monoclonal AntibodiesIBA 01/2012 - 07/2004
2	Hydroxyproline (4 Hydroxyproline)IBA 01/2024 - 10/2018
2	Ascorbic Acid (Vitamin C)FDA LinkGeneric 11/2023 - 04/2010
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2023 - 01/2021
2	osimertinibIBA 02/2023 - 01/2022
2	CollagenIBA 01/2023 - 02/2002
2	Prednisolone (Predate)FDA LinkGeneric 12/2022 - 01/2018
2	bu-zhong-yi-qi-tangIBA 09/2022 - 12/2018
2	Indicators and Reagents (Reagents)IBA 02/2021 - 01/2007
2	Interleukin-6 (Interleukin 6)IBA 01/2021 - 01/2017
2	Bronchodilator Agents (Bronchodilators)IBA 01/2021 - 03/2006
2	Small Interfering RNA (siRNA)IBA 01/2021 - 09/2018
2	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 01/2021 - 04/2013
2	Immune Checkpoint InhibitorsIBA 11/2020 - 09/2019
2	Amino Acyl-tRNA Synthetases (Aminoacyl-tRNA Synthetase)IBA 01/2019 - 12/2018
2	suplatast tosilateIBA 01/2019 - 01/2017
2	ChemokinesIBA 01/2019 - 01/2017
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 09/2018 - 03/2006
2	Docetaxel (Taxotere)FDA Link 09/2018 - 08/2007
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2017 - 02/2013
2	Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA 01/2016 - 02/2002
2	SK-216IBA 01/2016 - 01/2016
2	Leukocyte Elastase (Neutrophil Elastase)IBA 01/2014 - 01/2013
2	SugarsIBA 01/2012 - 07/2004
2	Tyrosine Kinase InhibitorsIBA 07/2011 - 06/2008
2	Tumor Biomarkers (Tumor Markers)IBA 10/2008 - 06/2008
1	Lipocalin-2IBA 05/2024
1	paquinimodIBA 01/2024
1	RNA (Ribonucleic Acid)IBA 11/2023
1	Hypoxia-Inducible Factor 1IBA 11/2023
1	NestinIBA 01/2023
1	GlucocorticoidsIBA 12/2022
1	Interleukin-13IBA 12/2022

Therapy/Procedure

21	Drug Therapy (Chemotherapy) 07/2022 - 02/2002
9	Therapeutics 01/2021 - 01/2004
7	Radiotherapy 11/2022 - 02/2002
5	Traction 02/2021 - 01/2018
3	Chemoradiotherapy 09/2021 - 10/2017
2	Oral Administration 10/2022 - 06/2017
2	Nebulizers and Vaporizers (Inhaler) 01/2022 - 09/2018
2	Catheters 01/2020 - 01/2018
2	Aftercare (After-Treatment) 06/2011 - 02/2005
1	Cell Transplantation 11/2023